Published On: Thu, Dec 6th, 2018

New 10mn cancer test

testResearchers from the university of Queensland in Australia have developed a 10-minute test that can detect the presence of cancer cells anywhere in the human body by discovering a unique DNA structure that appears to be common across cancer types.

Each cancer type has different genetic signature and a test that detects one cancer may not work on another, researchers have long been looking for a commonality among cancers to develop a diagnostic tool that could apply on every test.

When placed in water cancer DNA forms a unique similar structure among samples of breast, prostate and bowel cancers, as well as lymphoma.

Most detection of cancer uses usually a tissue biopsy or surgical procedure to collect tissue from the patient, the new test uses cancer DNA but with a different detection method.

Nearly every cell in a person's body has the same DNA and studies have found that cancer causes this DNA to reprogram the distribution pattern of a tiny molecule called a methyl group, in normal cell the methyl pattern regulates its machinery and maintains its functions, messing with this pattern is one of the ways cancer cells multiply.

This methyl patterning has been studied before but not in a solution such as water, using transmission electron microscopy (a high-resolution microscope), researchers saw that cancerous DNA fragments folded into three-dimensional structures in water different from normal DNA.

Gold particles are usually used in a lab to help detect DNA because gold can affect molecular behavior in a way that causes visible color changes.

They found that cancerous DNA strongly binds to the gold particles, they mixed a tiny amount of purified DNA with some drops of gold particle solution.

By simply observing the color change, it is possible to identify the cancerous DNA with the naked eye within five minutes, the test could also help monitor treatment responses based on the abundance of DNA signatures in body fluid during treatment.

The new technology has proved to be up to 90 percent accurate in tests involving 200 human cancer samples and normal DNA but more clinical trials on a larger scale is needed before it can be used on patients.

They're also looking into the possibility of using different bodily fluids to detect different cancer types from early to the later stages of the disease.

Maybe this is the holy grail for all cancer diagnostics as announced by a researcher.

© ReinaSankari 2018

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